km on Nostr: AI-text The brain primarily runs on glucose, which it consumes as its main and most ...

AI-text

The brain primarily runs on glucose, which it consumes as its main and most efficient energy source. Under normal physiological conditions, the brain extracts roughly 90% of its energy from glucose delivered through the bloodstream, accounting for about 20-25% of the body's total glucose usage despite making up only 2% of body weight.

While glucose is the obligatory fuel for most neural functions, the brain can adapt to use ketone bodies as an alternative energy source during fasting, starvation, or low-carbohydrate diets.
In these states, the brain can derive up to 70% of its energy from ketones, though it still requires a baseline amount of glucose (produced via gluconeogenesis) to function properly.

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